FILLERINA 12 HA DERMO-COSMETICS FOR SPECIFIC AREAS Fillerina 12 HA dermo-cosmetic filler preparations have been developed based on research, the result of which was the creation of special formulas suitable for specific facial areas.
Fillerina 12 HA dermo-cosmetic filler for specific areas has a modulated concentration with 12 different hyaluronic acid molecules with different molecular weights and sizes, which are particularly effective in penetrating the skin (ex vivo tests with Franz Cell), thus allowing it to be filled. The effect of hyaluronic acid is complemented by 3 collagens and 2 elastins, which strengthen skin tissues and create firmness. The molecules are calibrated to adapt to the skin of each specific facial area and to optimize the penetration of ingredients, as well as to provide filling, firming, and anti-wrinkle effects. Each product intended for a specific area has a different composition of active ingredients adapted to the specific area. An anti-wrinkle, firming, and filling effect is achieved.
VOLUME-INCREASING EFFECT
As the skin ages, the amount of hyaluronic acid gradually decreases, creating imperfections such as age-related wrinkles, expression lines, and loss of volume, especially in the cheekbone and lip areas.
Fillerina 12HA dermo-cosmetics contain patented 12 different hyaluronic acid molecules with different molecular weights and sizes, which are particularly effective in penetrating the layers of the skin (ex vivo tests with a cell diffusion device), thus allowing tissues to be filled and restored. The composition includes 12 types of hyaluronic acid with 12 different molecular weights, ranging from 400 to 2,000,000 Da, to modulate filling in different skin layers (ex vivo test).
DENSITY-INCREASING EFFECT
Fillerina 12HA dermo-cosmetics contain 3 collagen molecules with different molecular weights (2,000, 12,000 and 300,000 Da), which, penetrating into the dermis (ex vivo tests with a cell diffusion device) and thanks to hyaluronic acid molecules, can promote an increase in the density of the extracellular matrix and improve the volume-increasing effect.
Along with chronological aging, the amount and quality of elastin, the protein that forms elastic fibers, also decreases sharply, thus compromising skin firmness and promoting skin sagging. The formula contains 2 elastin molecules with different molecular weights (1,400 Da and 2,200 Da), whose purpose is to compensate for this loss and restore skin elasticity and plasticity.
TRANSDERMAL TECHNOLOGY
In order for Fillerina hyaluronic acid and functional molecules to penetrate into different layers of the skin, Labo researchers developed a patented Transdermal technology, based on the very small molecular size of active ingredients. This is the main condition to guarantee their penetration into the layers of the skin. Thanks to this controlled penetration, the active ingredients are truly effective. Transdermal penetration is possible using the new Labo technology, and it was tested using a cell diffusion device.
Fillerina formula: Swiss patent No. CH 705 713. Transdermal technology: Swiss patent No. CH 711 466
Fillerina 12HA dermo-cosmetic filler gel for the eye area and eyelids promotes the filling of wrinkles in the eye area and helps lift the eyelids. The product contains a modulated concentration with 12 hyaluronic acid molecules, supplemented with 3 different collagen and 2 elastin molecules to provide a firming effect and firmness to the eye contour and eyelid tissues. Acetyl Hexapeptide-30 provides an anti-wrinkle effect by reducing skin micro-contractions.
